Methodological Challenges of Digital PCR Detection of the Histone H3 K27M Somatic Variant in Cerebrospinal Fluid
Cell-free DNA (cfDNA) in body fluids is invaluable for cancer diagnostics.Despite the impressive potential of liquid biopsies for the diagnostics of central nervous system (CNS) tumors, 8x4.25 a number of challenges prevent introducing this approach into routine laboratory practice.In this study, we adopt a protocol for sensitive detection of the H